Dana Murzyn is a Canadian former professional ice hockey defenceman. Drafted out of the Western Hockey League (WHL), he was selected fifth overall by the Hartford Whalers in the 1985 NHL Entry Draft.

After signing with the Whalers to a multi-year contract in September 1985, he made the Whalers roster for the 1985–86 season. Murzyn recorded three goals and 26 points in his rookie season to be named to the NHL All-Rookie Team. The following season, he tallied nine goals and 28 points, which would remain personal bests for Murzyn throughout his NHL career. A prolific scorer in junior, Murzyn established himself as primarily a stay-at-home defender in the NHL, noted for his strength in dealing with opposing forwards in front of the net and in the corners.

After two and a half seasons in Hartford, he was dealt to his hometown Calgary Flames midway through the 1987–88 season. The following season, his first full campaign with the Flames, represented the highlight of his career, as he helped Calgary to a Stanley Cup championship in 1989, defeating the Montreal Canadiens in six games.

Murzyn remained with the Flames for two more seasons before being dealt to the Vancouver Canucks at the trade deadline on March 5, 1991. In Vancouver, Murzyn formed a partnership with the offensive Jyrki Lumme as the team's top defensive pairing. They later became the league's longest-enduring defensive pairing until Murzyn's retirement in 1999 after fourteen years in the NHL.